DRG 478 · Musculoskeletal

Bone & Muscle Biopsy (with complications)

A procedure to remove a small sample of bone, muscle, or connective tissue so it can be examined for infection, tumor, or other disease. The stay covers the biopsy plus care for related health conditions.

National avg charge
$87,601
gross · pre-insurance
Hospitals offering
1,793
across all 50 states
Hospitals with prices
352
have published MRF data
Lowest $8,248 Highest $323,876

Compare Bone & Muscle Biopsy cost by state

24 states with parsed pricing data, ranked by hospital count. More states roll out as we parse additional hospital MRF files.

What is bone & muscle biopsy?

A procedure to remove a small sample of bone, muscle, or connective tissue so it can be examined for infection, tumor, or other disease. The stay covers the biopsy plus care for related health conditions.

Bone & Muscle Biopsy is billed under Medicare's MS-DRG 478 (with complications), classified within the Musculoskeletal diagnostic category. Hospitals publish gross charges per DRG under the federal Hospital Price Transparency Rule, but actual cost depends on insurance: insurers negotiate substantial discounts, Medicare and Medicaid pay fixed rates, and uninsured patients can often qualify for cash-pay discounts. Use the gross charge as a benchmark when comparing hospitals; a facility that lists a procedure at twice the price of another tends to charge higher rates across the board.

Data current as of 2026-10-10.

Lowest published prices for Bone & Muscle Biopsy nationally

Top 100 by published price · 436 hospitals have published prices for this procedure. Check "Compare" on 2–3 hospitals to see them side by side.

Compare Hospital State CMS stars Gross charge Cash price
Randolph Hospital Asheboro, NC NC $8,248 —
MHP Major Hospital Shelbyville, IN IN $9,603 $3,073
Unity Medical Center Manchester, TN TN $9,906 $7,925
Suny/Downstate University Hospital of Brooklyn Brooklyn, NY NY $11,438 $11,438
Riverview Health Noblesville, IN IN $13,246 —
Springhill Medical Center (Acute Care) Mobile, AL AL $13,999 $13,999
Truman Medical Center Hospital Hill Kansas City, MO MO $14,195 $7,808
University Health Lakewood Medical Center Kansas City, MO MO $14,195 $7,808
Mary Lanning Healthcare Hastings, NE NE $14,369 $12,932
Oakbend Medical Center Richmond, TX TX $15,179 $3,036
Opelousas General Health System Opelousas, LA LA $15,196 $7,598
Putnam County Hospital Greencastle, IN IN $15,201 $12,921
Hendricks Regional Health Danville, IN IN $15,379 $6,152
San Joaquin General Hospital French Camp, CA CA $16,247 $8,936
Bacon County Hospital Alma, GA GA — $16,247 $12,997
Montgomery County Memorial Hospital + Clinics Red Oak, IA IA — $16,247 $11,373
Yalobusha General Hospital & Nursing Home Water Valley, MS MS — $16,247 $11,373
Doctors Hosptal at Renaissance Edinburg, TX TX $16,247 $16,247
UVA Health Emergency Department Prince William Medical Center Manassas, VA VA $16,499 $8,250
Vail Health Hospital Vail, CO CO $17,608 $13,206
South Central Reg Medical Center Laurel, MS MS $20,709 $8,698
Patients' Hospital of Redding Redding, CA CA — $21,092 $21,092
Heritage Valley Beaver Beaver, PA PA $21,777 $17,012
Heritage Valley Sewickley Sewickley, PA PA $21,777 $17,012
Holland Hospital Holland, MI MI $22,188 $13,313
Southwest Ms Regional Medical Center Mccomb, MS MS $22,646 $13,588
Lawrence County Hospital Monticello, MS MS — $22,646 $13,588
Island Hospital Anacortes, WA WA $24,225 $24,225
Mizell Memorial Hospital Opp, AL AL $24,778 $22,300
Mesa View Regional Hospital Mesquite, NV NV $25,497 $15,298
Rural Wellness Fairfax Fairfax, OK OK — $26,098 $15,659
UK St. Claire Morehead, KY KY $28,710 $21,533
Columbus Regional Hospital Columbus, IN IN $30,439 $24,351
William Newton Hospital Winfield, KS KS $30,565 $30,565
Mclaren Port Huron Port Huron, MI MI $30,708 $15,354
New York Community Hospital of Brooklyn, Inc. Brooklyn, NY NY $31,505 $31,505
Cobre Valley Regional Medical Center Globe, AZ AZ $31,534 $31,534
North Memorial Health - Robbinsdale Hospital Robbinsdale, MN MN $32,541 $17,149
North Memorial Health – Maple Grove Hospital Maple Grove, MN MN $32,541 $17,149
Ellis Hospital Schenectady, NY NY $35,214 $17,607
Cookeville Regional Medical Center Cookeville, TN TN $35,235 $21,599
Bassett Healthcare Cooperstown, NY NY $36,172 $9,767
Kenmore Mercy Hospital (Acute Care) Kenmore, NY NY $36,680 $36,494
St Francis Memorial Hospital West Point, NE NE $36,888 $36,888
Mercy Hospital Springfield Springfield, MO MO $36,888 $36,888
Astera Health Wadena, MN MN $36,942 $25,634
Memorial Medical Center Las Cruces, NM NM $37,040 $22,224
Mount St. Mary's Hospital Lewiston, NY NY $38,036 —
Sisters of Charity Hospital Buffalo, NY NY $38,036 —
Mercy Hospital of Buffalo Buffalo, NY NY $38,036 —
Pullman Regional Hospital Pullman, WA WA $38,429 $32,665
Lakewood Health System Staples, MN MN — $39,367 $24,407
Pineville Community Health Center Pineville, KY KY $40,289 $40,289
Genesis Hospital Zanesville, OH OH $40,398 $24,239
Duke Regional Hospital Durham, NC NC $41,591 $11,230
Valley Medical Center Renton, WA WA $42,034 $29,424
Hudson Regional Hospital New Jersey Secaucus, NJ NJ $43,071 $43,071
Sheridan Memorial Hospital Association Plentywood, MT MT — $43,442 $34,753
Sheridan Memorial Hospital Sheridan, WY WY $43,442 $34,753
Baxter Health Mountain Home, AR AR $43,648 $30,554
Christian Hospital Saint Louis, MO MO $43,718 $26,231
Thomas Hospital (Acute Care) Fairhope, AL AL $44,288 $23,540
Adventist Health Hanford Hanford, CA CA $45,632 $8,670
UVA Health Culpeper Medical Center Culpeper, VA VA $47,511 $23,755
Wayne Memorial Hospital Jesup, GA GA $49,419 $39,535
Wayne Memorial Hospital (Acute Care) Honesdale, PA PA $49,419 $39,535
Cambridge Health Alliance Cambridge, MA MA $50,122 $50,122
Progress West Hospital Ofallon, MO MO $51,171 $30,702
Adventist Health Delano Delano, CA CA $51,202 $10,240
Newton-Wellesley Hospital Newton, MA MA $52,587 $39,440
Community Howard Regional Health Kokomo, IN IN $52,871 $31,722
Community Hospital East Indianapolis, IN IN $52,871 $31,722
Community Hospital Anderson Anderson, IN IN $52,871 $31,722
Community Hospital South Indianapolis, IN IN $52,871 $31,722
Community Hospital North Indianapolis, IN IN $52,871 $31,722
Barnes-Jewish West County Hospital Creve Coeur, MO MO $53,420 $32,052
Hancock Regional Hospital Greenfield, IN IN $53,977 $43,182
Grand Island Regional Medical Center Grand Island, NE NE $54,011 —
Rochester General Hospital Rochester, NY NY $54,643 $35,518
RRH Clifton Springs Hospital & Clinic Clifton Springs, NY NY $54,643 $35,518
North Alabama Medical Center Florence, AL AL $55,006 $19,252
North Alabama Shoals Hospital Muscle Shoals, AL AL — $55,006 $19,252
Arnot Ogden Medical Center (Acute Care) Elmira, NY NY $55,415 $55,415
Rush Oak Park Hospital Oak Park, IL IL $55,475 $27,738
United Regional Health Care System Wichita Falls, TX TX $55,478 $52,704
St. Clair Hospital Pittsburgh, PA PA $55,601 $16,899
Southeast Georgia Health System-Brunswick Campus Brunswick, GA GA $56,297 —
Southeast Georgia Health System-Camden Campus Saint Marys, GA GA $56,297 —
Fairchild Medical Center Yreka, CA CA $56,661 $56,661
Christ Hospital Cincinnati, OH OH $56,741 $36,363
Westerly Hospital Westerly, RI RI $56,941 $20,499
Sarah Bush Lincoln Health Center Mattoon, IL IL $57,786 $57,786
Raleigh General Hospital Beckley, WV WV $58,827 $23,531
Swedish Hospital Chicago, IL IL $59,295 $38,542
Northshore University Healthsystem - Evanston Hospital Evanston, IL IL $59,295 $38,542
Stoughton Health Stoughton, WI WI $59,436 $32,690
Conway Regional Medical Center, Inc Conway, AR AR $61,479 $15,984
Ochsner Medical Center - Baton Rouge Baton Rouge, LA LA $61,624 $19,720
Hurley Medical Center (Acute Care) Flint, MI MI $61,768 $61,768
Haywood Regional Medical Center Clyde, NC NC $62,685 $25,074